Trimethoprim-Sulfamethoxazole in Murine Toxoplasmosis
نویسندگان
چکیده
منابع مشابه
Trimethoprim-sulfamethoxazole in murine toxoplasmosis.
The combination trimethoprim-sulfamethoxazole had no greater activity in a murine model of toxoplasmosis than did sulfamethoxazole alone.
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Sir—Toxoplasmosis is a disease that is highly transmissible to D ϩ /R Ϫ patients (i.e., patients who are seronegative for Toxoplasma gondii IgG antibodies and who receive a heart transplant from donors who are seropositive for T. gondii IgG antibodies). This disease, along with disseminated aspergillosis, is associated with the highest mortality rate attributable to an infectious complication i...
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The sulfonamides were the first drugs with antituberculous effects. Their use was abandoned and basically forgotten with the advent of streptomycin and isoniazid combination treatment. There is a widespread belief, apparently based on testing a single isolate on questionable media, that Mycobacterium tuberculosis is resistant to trimethoprim-sulfamethoxazole (TMP-SMX). We saw a complex immunoco...
متن کاملShort-term Results of Two Treatment Regimens in Ocular Toxoplasmosis: Trimethoprim/Sulfamethoxazole versus Pyrimethamine and Sulfadiazine
Purpose: To compare the efficacy of classic treatment for ocular toxoplasmosis (pyrimethamine, sulfadiazine and predinsolone) with a regimen consisting of trimethoprim/sulfamethoxazole (TMP/SMX) [co-trimoxazole] plus predinsolone. Methods: In a prospective randomized single-blind clinical trial, 59 patients with active ocular toxoplasmosis were randomly assigned to two treatment groups: 29 were...
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famethoxazole remains a popular antibiotic because of its low cost, effectiveness and familiarity among clinicians. It is the most frequently prescribed antibiotic for urinary tract infections in Canada. Other indications include treatment of infections caused by Pneumocystis jiroveci, Toxoplasma gondii, Stenotrophomonas maltophilia and community-associated methicillin-resistant Staphylococcus ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1976
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.9.2.222